No fewer than 10 key driver gene variants related to the pathogenesis of non-small cell lung cancer (NSCLC) have been developed, and many highly toxic and highly specific highly targeted drugs have been developed for these genetic abnormalities. Because of the relationship between these targeted drugs and genetic variation, it is like a key to open a lock. Therefore, accurate detection of lung cancer genes is a key prerequisite for ensuring that patients can reasonably choose the best targeted drugs.
How to do genetic testing? Most lung cancer patients usually undergo an invasive tissue biopsy (direct removal of fresh tumor tissue samples for examination). Such invasive biopsy has two major shortcomings: on the one hand, real-time dynamic detection on demand cannot be performed, and repeated biopsy can easily cause unnecessary damage; on the other hand, it usually takes several weeks to report results. A little long, may cause treatment delays. Some patients can't wait for a few weeks, and they need to start treatment before the genetic results come out. In this case, accurate targeted drug therapy may not be available in time.
How to improve the efficiency of lung cancer gene detection, accelerate the acquisition of test results, and then guide accurate targeted therapy earlier and in time has always been a major clinical challenge.
Recently, scientists turned their attention to liquid biopsy technology and successfully found a new method for detecting lung cancer genes by blood. Based on micro-drop digital PCR (ddPCR), DNA is divided into countless droplets. Specific circulating tumor DNA mutations and RNA variants in the whole blood were examined. It can accurately and quickly detect genetic mutations in non-small cell lung cancer, allowing patients and doctors to know the type of mutation earlier, select relevant targeted drugs in time, and finally achieve individualized and accurate anticancer treatment. The scientific journal "Journal of Molecular Diagnostics" published these important results.
This makes a lot of sense! Activating mutations in tumors are the main driving force in the pathogenesis and progression of tumors. Therefore, timely detection of these mutations and targeted use of targeted drugs can improve the therapeutic effect and reduce the risk of death.
â–²Microdrop digital PCR technology
1-Piece Ostomy pouch MDK-BO-01 800ML
A one-piece colostomy bags, drainable pouching system designed to be opened at the bottom when emptying. These colostomy bag machine are most suitable for colostomies or ileostomies. Ostomy bag colostomy barrier is a standard wear skin barrier that is gentle to the skin and allows for frequent pouch removal. To close the pouch, use the curved, beige clamp. Soft, beige disposable colostomy bag pouch panels on body side help provide comfort.
The features are soft and flex,standard wear, skin barrier, flat. The Chassis made in 100% hydrocolloid No tape border. Cut-to-fit skin barrier. Ultra-clear odor-barrier pouch film. Curved, beige pouch clamp. With comfortable ware pouch panel body side only. Not made with natural rubber latex.
Ostomy urostomy colostomy bag care products consist of sodium carboxymethylcellulose, adhesives made from medical hot melt adhesives, and separator paper or separators. Nursing equipment for ileum, colon, rectum or urethral stoma,The coloplast colostomy bag comes into contact with intact skin and intestinal lumen,Non-sterile supply. Colostomy bag reusable for stoma washing, care and collection of excreta and skin care around the stoma.
Use disposable colostomy bag, make sure the skin around the stoma is clean and dry before use. Remove the bags for colostomi from the package and separator or paper. Reshape the coloplast colostomy bag into the desired shape and size to fit the skin around the stoma. Apply the colostomy convatec bag to the skin around the stoma,adjust the shape of the paste again,Gently press so that it is firmly flat on the skin. Attach the stoma colostomy bag undercarriage to the stoma. The colostomy bag care can be peeled off the skin, don`t reuse. These one-piece-colostomy bag or two-piece-colostomy-bag are non-sterile product and is valid for three years under the condition of meeting the storage conditions.
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