Release date: 2018-02-11
Recently, scientists from NIH have developed a rapid early detection of redness in neurodegenerative diseases, including Alzheimer's disease. In this study, the authors examined 60 cerebrospinal fluid samples, 12 of which were Parkinson's, 17 of which were dementias with Lewy bodies, and 31 of whom were healthy. The authors found that this test method can accurately exclude the risk of illness in 31 healthy people, and the accuracy of diagnosis of Parkinson's disease and dementia is also 93%.
Importantly, this test result can be given in two days, which is 11 days higher than conventional tests. The results are published in the latest issue of Acta Neuropathologica Communications.
Most neurological disorders, including Parkinson's disease and dementia in the presence of Louise's body, have an abnormal deposition of proteins called alpha-synuclein in the brain, which form the Lewy body in the brain. The pathological course of the disease is very similar to the prion disease in mammals. Similar to prion diseases, Parkinson's disease and dementia can lead to disorders of brain function and eventual death. In fact, the incidence of Parkinson's disease in human population is 1000 times that of prion diseases. The number of Parkinson's patients in the United States has reached 1 million, and the number of newly diagnosed patients has reached 60,000.
Early and accurate diagnosis of these brain disorders can help develop protocols for identifying and treating related diseases. These diseases often begin several years before the onset of symptoms, and it is often difficult to accurately distinguish the type of disease in the early stages.
In the future, researchers plan to continue to optimize RT-QuIC detection methods to detect more types of neurological diseases and improve the accuracy of diagnosis.
Source: Bio Valley
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