Use of microencapsulation technology in probiotics

Microcapsule technology is a kind of micro- or nano-scale micro-particle products, which uses natural or synthetic polymer materials as micro-capsule wall materials to encapsulate solid and liquid pharmaceuticals, foods and chemical raw materials into capsule core materials. New technology, new technology. Has been applied in many fields such as medicine, food, fine chemicals (see Figure 1). The physiological and health functions of probiotics include: prevention and treatment of various stomach and intestinal diseases, enhancement of immune function, prevention and treatment of cancer, lowering of cholesterol, maintenance of intestinal flora balance and nutritional functions. However, when the country stipulates that probiotic products are shipped from the factory, the live bacteria content must be higher than 10 6 cfu/ml. however. Probiotics such as Lactobacillus and Bifidobacteria are mostly anaerobic or facultative anaerobic bacteria. During the growth process, no spores were formed, and the resistance was poor. Most of them were poor in acid resistance, extremely sensitive to oxygen, and the activity remained difficult to return. The number of viable bacteria in products that enter the market will drop dramatically. The storage stability of the product is extremely poor, and the health care effect is lost quickly. Microencapsulation technology can effectively solve this problem.

Figure 1 Microencapsulation of various substances

Microencapsulation technology uses a film forming material. The combination of embedding and freeze-drying organically forms a protective film similar to microcapsules around the living cells of the probiotics while lyophilizing, thereby embedding the probiotic bacteria in the protective film, thereby reducing or even Avoid bacterial freeze-drying damage. Protect probiotics from phage, increase the survival rate of live bacteria, and prolong the storage period of live bacteria at room temperature.

Figure 2 MP-180 high-pressure microcapsule forming device produced by Shanghai Baosheng Company

There are many ways to entrap probiotics in microcapsules, and the MP-180 high-pressure microcapsule molding device (see Figure 2) produced by Shanghai Baosheng Company uses high-voltage electrostatic method to prepare microcapsules, which can produce microcapsule particles. Very uniform product. This will play a positive role in promoting the production of probiotic live bacteria preparations and probiotics series products, opening up a new field of probiotic live bacterial preparation preservation technology.

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