Bacterial transplantation can alleviate adverse reactions in immunotherapy
November 23, 2018 Source: Science and Technology Daily Author: Zhang Meng Ran
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];According to a recent medical study published by the British journal Nature Medicine, American scientists treated two cancer patients with severe colitis caused by immunotherapy by transplanting intestinal bacteria from healthy donors.
In recent years, immunotherapy has revolutionized cancer treatment. This tumor-specific immunotherapy aims to activate the body's immune system and rely on autoimmune functions to kill cancer cells and tumor tissue. Unlike previous surgery, chemotherapy, radiotherapy, and targeted therapy, immunotherapy targets are not tumor cells and tissues, but the body's own immune system. Despite a series of successes in related research, immunotherapy is often accompanied by severe immune-related toxicity that is harmful to patients, which can lead to treatment interruption.
One of the adverse reactions is colitis, which is an infection of the inner wall of the colon. It can be caused by bacteria, fungi, viruses, parasites, protozoa, etc. It can also be caused by allergies and physical and chemical factors. Colitis, which is an adverse reaction, is considered to be It is related to changes in intestinal flora in patients receiving immunotherapy. In view of this, Wang Yinghong, a scientist at the MD Anderson Cancer Center at the University of Texas, and his colleagues, transplanted the fecal microbiota from healthy donors to two cancer patients with colitis after immunotherapy. The results showed that the symptoms of colonic inflammation were alleviated in the patients after transplantation.
The research team also collected the patient's stool samples before and after transplantation, and found that the transplant can indeed restore the protective bacteria of the intestinal flora and alleviate the inflammation associated with colitis.
Although this result is yet to be confirmed in a larger patient population and clinical trials, the research team confirmed the possibility of responding to major adverse effects of cancer immunotherapy through fecal transplantation.
Matcha, originated from China, is finely ground powder of specially grown and processed green tea.
It is special in two aspects of farming and processing: The green tea plants for matcha are shade grown for about three weeks before harvest, and the stems and veins are removed in processing.
The traditional Chinese tea ceremony centers on the preparation, serving, and drinking of matcha. In modern times, matcha also has come to be used to flavour and dye foods such as mochi and soba noodles, green tea ice cream,etc.
It`s a special form of green tea:
Matcha literally means powdered tea." When you order traditional green tea, components from the leaves get infused into the hot water, then the leaves are discarded. With matcha, you`re drinking the actual leaves, which have been finely powdered and made into a solution, traditionally by mixing about a teaspoon of matcha powder with a third cup of hot water (heated to less than a boil), which is then whisked with a bamboo brush until it froths.
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