Medications need to be alert to categories, doses, these drugs or deafness!

[ China Pharmaceutical Network Health and Wellness ] It is reported that during the flu period, some parents have cured their children's colds earlier, giving their children adult drugs or not paying attention to the categories, which caused some children to have serious consequences of deafness. According to industry statistics, due to improper medication, about 30,000 children are trapped in the silent world every year, causing the number of liver and kidney functions, nervous system and other injuries, and parents must pay attention to it, cautious use of drugs, dosage.

The authors query and organize according to the relevant information, the following antibiotics or non-antibiotics or deafness, severe or permanent, light can be recovered after stopping the drug.

Antibacterial drugs

As early as 1999, the state promulgated the "Clinical Use Specifications for Common Ototoxic Drugs", and announced 30 drugs that are prone to deafness, including some commonly used antibacterial drugs, such as streptomycin, gentamicin, and kanamycin. , small noromycin, erythromycin, chloramphenicol, vancomycin hydrochloride.

In China, the misuse or abuse of aminoglycoside antibiotics is the primary cause of congenital and acquired deafness in newborns and adult deafness.

--lactam drugs. Penicillins such as ampicillin and cloxacillin, as well as cephalosporins such as cephalexin, cefazolin, and cefradine, can also cause adverse reactions of tinnitus or hearing loss.

Tetracyclines. For example, high-dose minocycline can cause dizziness, tinnitus, ataxia, nausea, vomiting, etc., but these drugs can be recovered after 24 to 48 hours of withdrawal.

Macrolides. For example, erythromycin can cause adverse reactions to tinnitus and hearing impairment, especially when administered intravenously, and withdrawal or reduction can be restored.

Glycopeptides. For example, large doses and long-term use of vancomycin, norvancomycin, teicoplanin, etc. can produce dose-dependent tinnitus and irreversible hearing damage.

Antifungal drugs. The industry said that long-term high-dose use of griseofulvin can cause tinnitus and deafness with unknown mechanism, and the symptoms can disappear after stopping the drug.

Non-antibiotic drugs

Diuretic drugs. Such as diuretic acid, furosemide, butyl benzoic acid, etc., when the use of larger doses will occur ear damage, so the use of diuretic drugs need to be cautious, follow the doctor's advice and rational use of drugs. However, the damage of hearing pills caused by furosemide drugs is hidden, and it is necessary to pay attention to it, and it may be restored after stopping the drug in time.

Beta blockers. For example, β-blockers such as Xinninging, Xindean, chlorthalidone, metoprolol, and hydralazine may cause sputum toxicity.

Salicylic acid drugs, represented by aspirin, may cause headaches, dizziness, tinnitus, deafness and other side effects when used up to 6-8 grams per day. Although most of the patients' deafness can gradually disappear in 48 hours, a small amount of damage can not be recovered.

Antimalarial drugs, such as quinine and aminoquine, are also at risk. Among them, quinine causes tinnitus, heavy hearing and other reactions at the therapeutic dose, and large doses may cause paralysis and permanent damage, which cannot be recovered. However, long-term use of chloroquine may cause permanent deafness.

Some anticancer drugs also have a risk of causing convulsions. For example, if a large dose of nitrogen mustard is applied, the higher the blood concentration will damage the inner ear cells or cause the sensorineural deafness; the large dose of cisplatin for gynecological tumors may cause sudden deafness, but this Most of the drugs are reversible damage, which can be gradually recovered after stopping the drug.