Abstract: Vacuum is the driving force for collecting blood from vacuum blood collection tubes, which directly affects blood collection. In this paper, Labthink the G2 / 130 container gas pressure method for air permeability tester vacutainer samples were tested permeation amount, the blood collection tube to prevent air causes a change in the degree of vacuum inside thereof through excessive, The test equipment, test principle, equipment parameters and other content are introduced to provide reference for enterprises to monitor the air permeability of vacuum blood collection tubes.
Key words: vacuum blood collection tube, vacuum degree, blood collection volume, barrier property, air permeability, differential pressure method, gas permeability tester
1. significance
Vacutainer tube plug generally consists of four parts, plastic caps, tubes and additives, having a clean and safe, simple and reliable when used in blood collection process has been widely used in the world. According to the different blood analysis applications, the types and concentrations of additives contained in the vacuum blood collection tube will be different, and the color of the blood collection tube hat is distinguished, as shown in Figure 1 .
Figure 1 Vacuum blood collection tube for different purposes
There are many factors affecting the quality of vacuum blood collection tubes, such as the type, performance, concentration and vacuum stability of materials and additives for vacuum blood collection tubes. Vacuum is the driving force for blood collection in vacuum blood collection tubes. The degree of vacuum directly affects the blood collection tubes. Blood collection. The quality of venous blood collection depends on the ratio of blood to anticoagulant. For vacuum blood collection tubes, the ratio of blood to anticoagulant depends on the blood collection volume of the blood collection tube. If the blood collection volume is high, the blood ratio is too high. The coagulant is relatively insufficient, and the microcoagulation in the plasma increases rapidly, which may block the test instrument and affect some test indicators. If the blood collection amount is small, the anticoagulant is relatively excessive, which will also seriously affect the test. Therefore, the degree of vacuum in the vacuum blood collection tube is an important factor affecting the detection results. For the degree of vacuum in the blood collection tube, in addition to the air pressure of the ambient pressure, temperature and vacuum tube, the barrier property of the blood collection tube to the air in the environment is also one of the influencing factors, and the higher air permeability will lead to the edge. The amount of gas infiltrated into the blood vessel is high, which causes the vacuum degree of the blood collection tube to decrease, and as the storage time of the blood collection tube is prolonged, the influence of the poor barrier performance on the vacuum degree will become more and more obvious, so the vacuum is enhanced. Monitoring of vascular barriers is particularly necessary.
2. Test samples
A brand of plastic vacuum tube.
3. Detection basis
In the storage process, there is a pressure difference between the inner and outer sides of the vacuum blood collection tube. Therefore, the air permeability of the vacuum blood collection tube sample is tested by the differential pressure method. At present, there is no measurement of the gas permeation of the container by the differential pressure method. Related standards.
4. Test equipment
In this paper , the air permeability of the sample is tested by the G2/130 differential pressure method gas permeability tester independently developed by Jinan Languang Electromechanical Technology Co., Ltd.
Figure 2 G2/130 differential pressure method container gas permeability tester
4.1 Test principle
When the air permeability of the container is tested by the principle of differential pressure method, a certain pressure difference is maintained on both sides of the sample. During the test, the processed hollow container sample is clamped on the test chamber, and then the inner and outer chambers of the container and the whole system are evacuated to a predetermined degree of vacuum, then the vacuum is stopped, and then the outer chamber of the sample is placed. Introducing pure air, so that the set pressure difference is reached between the inner and outer chambers. Under the action of the differential pressure gradient, the air will penetrate into the inner cavity through the sample outside the sample cavity, and the monitoring according to the pressure change of the inner cavity Obtain air permeability performance data of the entire container sample.
4.2 Equipment parameters
- The test range is 0.0001 ~ 1800 mL / (pkg · day) and the vacuum resolution is 0.1 Pa .
- 3 can be simultaneously tested sample gas transmission amount, and displays the average results of three test specimens.
- The test temperature is ambient temperature, and the humidity control range is 0% RH , 2% RH ~ 98.5% RH , 100% RH .
- Test gases that can be tested include air, oxygen, nitrogen, carbon dioxide, and the like.
- The inner and outer chambers of the container are vacuumed to ensure the accuracy and effectiveness of the test data.
- The system is computer controlled and the entire test process is done automatically.
- Support Lystem TM laboratory data sharing system to manage test results and test reports.
- The invention patent test method and structural design effectively solve various problems in the test of the differential pressure method container.
4.3 Scope of application
The device is suitable for testing the overall gas permeation of various hollow packaging containers, such as carbonated beverage bottles, fruit bottles, edible oil drums, tea beverage bottles, dairy packaging containers, washing product packaging containers and metal packaging containers.
5. Test process
(1) Seal the vacuum blood collection tube to be tested with the quick-fixing glue on the sample clamping structure of the device, and fix the sealing cover.
Figure 3 sample is completed
(2) Set the sample name, sample parameters and other related information.
(3) Click the test option to turn on the vacuum pump and the test starts.
(4) After the test is over, the device automatically displays the test results.
6. Test results
The air permeation volume of the vacuum blood collection tube sample tested in this test was 0.0061 mL/(pkg·day) .
7. Conclusion
Air permeability is an important factor affecting the blood collection of vacuum blood collection tubes, which directly affects the accuracy of the test results. Therefore, the monitoring of its barrier performance should be strengthened. The G2/130 differential pressure method gas permeability tester has the advantages of accurate test results, good repeatability, simple operation, etc., and can test a variety of gases, which is an accurate test. A test device for the barrier properties of a container sample. Labthink is a high-tech enterprise specializing in the R&D, production and service of packaging inspection equipment. It is committed to providing high-end and precise packaging inspection equipment and intimate and high-quality packaging inspection services to customers all over the world. Relevant testing equipment has been covered. The package's barrier performance, smoothness, flexibility, sealing performance, puncture resistance and solvent residue, evaporation residue and other comprehensive performance testing, related equipment and services can be viewed at Jinan Languang Company or call Jinan Languang Consulting . The more you understand, the more you trust! Labthink is looking forward to enhancing technical exchanges and cooperation with enterprises and institutions in the industry!
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