A meat duck farm in Yilan County was diagnosed with H5N2 highly pathogenic avian influenza on the 4th. On the morning of the 5th, the anti-epidemic staff culled about 6,000 ducks and carried out field disinfection. In addition, in areas such as Changhua and Pingtung, bird flu epidemics were re-introduced and thousands of ducks were culled.
Taiwan's agricultural authorities said on the 5th that there were 3 newly diagnosed H5N2 subtypes of high-pathogenic avian influenza cases on the day of poultry farms, and completed 2 culling and epidemic prevention measures. Since the beginning of this year, poultry farms have diagnosed a total of 74 cases of highly pathogenic avian influenza and completed the culling of more than 560,000 poultry. There was no new confirmed case of H5N6 on the 5th. So far, the H5N6 confirmed poultry farm has maintained 11 sites.
Taiwan's agricultural authorities pointed out that in order to detect potential bird flu viruses as soon as possible and eliminate them in real time, a number of innovative practices were initiated, including embargoes, culling and compensation, encouragement notifications, and the implementation of pre-market duck virus testing. The number of confirmed cases of culling has increased significantly, but most of them are sporadic, and the epidemic is currently under stable control. (Source: Beijing Daily)
API Powder is fully defined in ICH Q7A as any substance or mixture of substances intended for use in the manufacture of pharmaceutical products and, when used in pharmaceutical products, as an active ingredient of pharmaceutical products. Such substances have pharmacological activities or other direct effects in the diagnosis, treatment, symptom relief, management or prevention of disease, or can affect the function or structure of the body. The active ingredient of a medicine. Only when an API is processed into a pharmaceutical preparation can it become a medicine for clinical application.
According to its source, apis are divided into chemical synthetic drugs and natural chemical drugs.
Chemical synthetic drugs can be divided into inorganic synthetic drugs and organic synthetic drugs. Inorganic synthetic drugs are inorganic compounds (very few are elements), such as aluminum hydroxide and magnesium trisilicate for the treatment of gastric and duodenal ulcer, etc. Organic synthetic drugs are mainly made of basic organic chemical raw materials, through a series of organic chemical reactions and drugs (such as aspirin, chloramphenicol, caffeine, etc.).
Natural chemical drugs can also be divided into biochemical drugs and phytochemical drugs according to their sources. Antibiotics are generally produced by microbial fermentation and belong to the category of biochemistry. In recent years, a variety of semi-synthetic antibiotics are the combination of biosynthesis and chemical synthesis products. Among apis, organic synthetic drugs account for the largest proportion of variety, yield and output value, which is the main pillar of chemical pharmaceutical industry. The quality of the API determines the quality of the preparation, so its quality standards are very strict. All countries in the world have formulated strict national pharmacopoeia standards and quality control methods for the widely used APIS.
Specific API after processing -- pharmaceutical preparations
The term API is used mainly in relation to the finished product. Mainly raw materials obtained by chemical processing means, supply raw materials for the production of finished drugs. For example, cefpirome sulfate for injection is a drug, then cefpirome sulfate is an API
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