Release date: 2016-11-30
The National Institutes of Health announced on the 28th that the first clinical trial of AIDS vaccine effectiveness has been launched in South Africa since 2009. As a sponsor of this trial, the agency hopes that the tested AIDS vaccine portfolio will be able to complete the "fatal" of HIV. one strike".
The National Institutes of Health issued a statement on the same day saying that the AIDS vaccine combination called HVTN 702 consists of a vaccine that stimulates the immune system and a vaccine that boosts the immune response. Researchers will recruit 5,400 healthy adults between the ages of 18 and 35 who are at high risk of infection in 15 locations in South Africa. This is the largest AIDS vaccine clinical trial ever conducted in South Africa.
Anthony Foch, director of the National Institute of Allergy and Infectious Diseases under the National Institutes of Health, said: "If used with other proven HIV prevention tools in our existing arsenal, a safe and effective vaccine will It is possible to complete a fatal blow to HIV. Even moderately effective vaccines will significantly reduce the burden on countries with high rates of HIV infection, such as South Africa."
HVTN 702 was improved from the AIDS vaccine RV144 that completed clinical trials in Thailand in 2009. During a three-and-a-half-year clinical trial, RV144 is 31% effective and is the first AIDS vaccine to provide protection for some people. Researchers hope that HVTN 702 will provide more effective and lasting protection than RV144.
HVTN 702 has adapted to the prevalence of HIV subtypes in southern Africa. Each participant was vaccinated five times a year and randomized to vaccination or placebo. The results are expected to be announced in the second half of 2020.
Previously, a small study involving more than 200 people has proven that HVTN 702 can be safely used in humans.
Since the advent of AIDS, the development of an effective AIDS vaccine has been one of the goals pursued by the scientific community, but its progress has been slow.
Source: Xinhuanet
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