The pretreatment process of traditional Chinese medicine generally includes the steps of selecting, washing, purifying, cutting, drying and pulverizing the medicinal materials; the extraction process generally includes extraction, concentration, separation (alcohol precipitation/water sedimentation, filtration, centrifugation) and the like. Equipment selection should be carried out according to mainstream products and production processes, and equipment should be used correctly according to the performance and working principle of the equipment. Through the process, it can be seen that in the pre-treatment stage, the quality of the drug and the production cost have been basically finalized. If the production process and equipment performance are not well combined, problems such as unstable product quality, high raw material consumption, and high production cost will occur during the production process. After the processing of the pre-treatment and extraction processes, the medicinal material becomes an intermediate of the drug, and the Zui becomes a drug. The pretreatment and extraction process of traditional Chinese medicine is a key process in production, and it is also a process that Zui is easily overlooked by managers. Equipment operators do not understand the working principle of the equipment, and it is impossible to use the equipment correctly. Therefore, the organic combination of equipment and production processes and the correct use of equipment are an important part of improving quality and efficiency.
1, washing machine
The surface of the medicinal herbs (Chinese Herbal Pieces) has not only mud and other debris, but also a large amount of mold. The purpose of the drug is to remove the sediment and most of the mold. At present, most pharmaceutical companies use roller-type washing machines to wash drugs with spray water. Some enterprises use different speeds and water to clean the medicinal materials. When the leaves, stems, roots and slices are used, different cleaning effects will occur.
The washing machine should wash different medicines with different speeds and water spray according to different varieties. Under the premise of washing, try to shorten the time of washing and avoid the loss of active ingredients. It can be modified for the drum type washing machine, and the speed regulating device and the pressurizing device are added to adopt different cleaning methods for different medicines.
2, the drug machine
At present, most Chinese medicine pharmaceutical companies are using water-filled vacuum drugs. The working principle of the vacuum moisturizer: vacuum is used to extract the air in the voids of the medicinal fiber, and the water rapidly enters the plant cell tissue through the capillary under negative pressure conditions. The purpose of the medicinal herbs is to allow the dehydrated plant cells to absorb the water from the imported pump, and to create conditions for the extraction process, because the active ingredients in the medicinal materials are generally exchanged under the action of water (or other solvent). Among them, the control of the degree of vacuum can achieve good penetration effect of Zui; control the amount of water can prevent the loss of active ingredients; control the time of the drug can reduce the enzymatic hydrolysis of the active ingredients (there are some corresponding hydrolase in some glycosidic cells, time passed Long partial glycosides will be hydrolyzed).
The use of the drug-running machine should pay attention to: (1) determine different vacuum degrees and time according to different medicinal materials; (2) determine different water addition amount according to different medicinal materials, try to achieve water and drug penetration.
The old-fashioned medicine machine is a water-filled vacuum medicine machine. Due to the poor effect of the medicine, it has been replaced by the vapor phase type medicine machine in recent years. Old equipment can use operation skills to make up for equipment defects. In order to ensure the degree of vacuum, the vacuum can be reduced to Zui in three times (ie, pulsation 3 times), and the water injection pipe can be changed into a drip tray. Improved.
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