In a recent interview, the author learned that in the detection and analysis of DNA, protein and protein analysis techniques used in viruses, pathogens, and cancer, electronic technology has now begun to be fully adopted.
The relationship between electronics, especially semiconductor technology, and biological and chemical technologies is much closer than I thought, and will be further integrated in the future. In addition, the impact of convergence is enormous, and can even be said to be destructive. Through interviews, I believe that the integration of the two will become a source of income for many businesses in the future. Although the market has not yet officially expanded, there will be tens of billions of yen-scale inspection techniques in the next few years.
Engineers can easily understand DNA technology
To be honest, the author once disagreed with biology. Speaking of it, maybe because the author did not learn Mendel's law in high school, it is considered that biology is a very complicated subject that needs to be memorized. The author's major is physics and its application, but I do not know why many Japanese biologists reject the reduction theory and the scientific view of increasing knowledge through research and experiment, which is why the author contradicts biology.
However, there are several biotechnologies abroad, especially those related to DNA, which are very similar to physics and engineering studies. The "double helix" (Talks Library, 1986), which I read in the student era and was discovered by DNA discovery (JD Watson), is a very interesting book. This is both a great research note, and it allows the layman to read like the best mystery novels, and experience the thrills and excitement of research. The author did not feel the gap between physics, engineering and biology.
In order to write a report, the author has a general understanding of some DNA related research results. Through learning, the author also realized that DNA and its role is actually an information communication technology that translates "design information of life" into protein synthesis. DNA also has mechanisms equivalent to communication coding and error correction techniques. DNA analysis technology is similar to existing communication technologies. For example, first amplify the weak signal and then analyze it.
Progress faster than supercomputer
The progress of DNA analysis technology is also very similar to computer and semiconductor technology. For example, analytical techniques have dramatically increased speed. The "DNA sequencing" of the interpretation of the 3 billion base pair sequences in human DNA used most of the human tactics before the 1990s. I have a college student who is engaged in DNA research and often complains that there is no time to sleep.
After the 2000s, the automation and parallelization of the analysis program developed rapidly. "The analysis speed has increased by about 10 times in 2 years." Then 10 years will increase 100,000 times. In one and a half to two years, semiconductor technology has doubled its integration and performance, and the speed of supercomputers has increased by about 4 times in 2 years and about 1000 times in 10 years. This shows that the progress of DNA analysis technology has improved. How fast. In the 1990s, it took several years to interpret all the base pairs of human DNA, but now it takes only 1-2 days to complete.
The miniaturization in the "laboratory" is the same as that of semiconductors
However, until a few years ago, DNA analysis techniques were mostly chemical methods. Chemical inspection techniques continue to be “micronizedâ€, and the work of shaking test tubes in the past has gradually been replaced by “lab-on-a-chip†technology built on the chip in the entire laboratory, and has also promoted DNA analysis. Great advances in technology. However, even if the interpretation time is shortened, the miniaturization speed of the optical analysis device used cannot be shortened as fast as the analysis time. Up to now, most of the main analytical devices are as large as large wardrobes, and the instruments that can be placed on the table are very small.
Recently, electronic technology has finally entered the field of biology, breaking the conventional knowledge of the device, greatly reducing the size of the product and improving the accuracy. For example, in 2012, the DNA analysis device launched by Oxford Nanopore Technologies in the United Kingdom was about the same size as the USB flash drive.
The participation of electronic technology was achieved after the miniaturization of chemical technology. Although the work of shaking the test tube is not related to electronic technology, the lab-on-a-chip technology can naturally understand that the work depends on the semiconductor chip. By the way, the flu virus is about 100 nm in diameter, just like the semiconductor design rules 10 years ago.
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